Journal: JAC-Antimicrobial Resistance
Article Title: Cefepime-zidebactam therapy for extensively drug-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae infection as a bridge to liver transplantation
doi: 10.1093/jacamr/dlaf129
Figure Lengend Snippet: Clinical timeline, culture results, and antimicrobial therapy. Day of transplant is given as day zero. Antimicrobials are shaded by class/spectrum: blue, β-lactams and β-lactam/β-lactamase inhibitors; orange, tetracyclines; green, antibiotics with Gram-positive activity only; purple, antifungals. CR, carbapenem-resistant; ESBL, extended spectrum β-lactamse; ERCP, endoscopic retrograde cholangiopancreatography; IMP, active-on-imipenem; MDR, multidrug-resistant; NDM, New Delhi Metallo-β-lactamase; OXA, oxacillinase; PTC, percutaneous transhepatic cholangiography.
Article Snippet: Antimicrobial susceptibility testing was performed in triplicate via broth microdilution at Johns Hopkins University School of Medicine using frozen antimicrobial panels in accordance with Clinical and Laboratory Standards Institute (CLSI) guidelines with interpretive criteria based on the M100 35th edition published in 2025.
Techniques: Activity Assay